An Inquiry into the Causes and Effects of the Variolae Vaccinae, a Disease Discovered in Some of the Western Counties of England, Particularly Gloucestershire, and Known by the Name of the Cow Pox.

iv, 75 pp. 4to. Original green cloth, paper labels. Facsimile reprint of the 1798 original, published 125 years later, on the 100-year anniversary of Edward Jenner's death. 4 color plates. Garrison-Morton 2529.3 and 5423: "Jenner established the fact that a 'vaccination' or inoculation with vaccinia (cowpox) lymph matter protects against smallpox. What is probably the first mention of anaphylaxis appears on p. 13... He performed his first vaccination on May 14, 1796. The above work, describing 23 successful vaccinations, announced to the world one of the greatest triumphs in the history of medicine. Jennerian vaccination soon superseded the protective inoculation of material from human cases of smallpox, which had previously been in vogue... Several facsimile editions have been published. As a result of the success of Jenner's vaccine natural smallpox was eradicated. The official declaration was made by the World Health Organization on May 8, 1980."